Interferon gamma, IFN-γ, is a major immune-modulating moleculeproduced mainly by T-cells and natural killer cells activated byantigens, mitogens or alloantigens. Most immune cells expressIFN-γ receptors and respond to IFN-γ-induced signaling byup-regulating MHC class I expression. Recombinant rat IFNgamma is a non-glycosylated protein, containing 135 amino acidsand has a predicted molecular weight of 15.6 kDa.
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