Capacity:for1×109totalcellsOverview
Anti-HLA-DRMicroBeadshavebeendevelopedforpositiveselectionordepletionofantigen-presentingcellsfromPBMCs,cordblood,bonemarrow,andtissue.
Details
Backgroundinformation
TheHLA-DRantigenisconstitutivelyexpressedonprofessionalantigen-presentingcells(dendriticcells,Bcells,monocytes/macrophages),anditsexpressionisfurtherup-regulateduponactivation.OnTcells,NKcells,hematopoieticprecursorcells,andsomeepithelialcellstheexpressionofHLA-DRisinducedbycellactivation.
Downstreamapplications
HLA-DR–positivecellsareisolated,forexample,for
SEROlogicaltypingofHLAclassIImoleculesorstudiesonantigenpresentation.
Columns
Forpositiveselection:MS,LS,XS,orauto
MACS?Columns.Fordepletion:LD,CS,D,orautoMACSColumns.