Capacity:for1×109totalcellsOverview
Anti-DC(OX62)MicroBeadshavebeendevelopedforthepositiveselectionordepletionofOX62+dendriticcells(DCs)fromblood,lymphoid,andnon-lymphoidtissue.
Details
Backgroundinformation
ThemonoclonalantibodyOX62recognizestheintegrinαE2subunit(molecularmass:150kDa).OX62isexpressedonthe
CD4+andtheCD4-subsetofdendriticcellsbutnotonplasmacytoiddendriticcellsinlymphoidtissueoronepidermalLangerhanscells.OX62isalsofoundonasubpopulationofepidermalTCRα/β+orTCRγ/δ+Tcellsandonasubsetoffolliculo-stellate-like(S100+)cellsintheanteriorpituitary.Itisnotexpressedonmacrophages.
Downstreamapplications
IsolatedOX62+dendriticcellswereused,forexample,foranalysisofthedifferentialphenotype,function,andmigrationofdendriticcellsubsets.1
Columns
Forpositiveselection:MS,LS,XS,orauto
MACS?Columns.Fordepletion:LD,CS,D,orautoMACSColumns.