Lipid raft fractions isolated from adult rat brain. Target identified as Neurofascin by: - binding to NF-186-tranfected COS cells - recognition of NF155 and NF186 but not other highly related L1 CAMs like NrCAM - immunoprecipitation of NF155 and NF186 and confirmation by mass spectrometry - loss of immunostaining against NF186-shRNA knockdown samples Rat: amino acids 25-1110 (extracellular domain common to NF155 and NF186) Mouse: 98% identity (1074/1086 amino acids identical) Human: 79% identity (955/1195 amino acids identical) This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.