Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | DNA-PK(Phospho-Ser2056)Antibody |
Synonyms | DNA-PKcs;DNA-dependentproteinkinasecatalyticsubunit;DNPK1;P460;PRKD;PRKDC;XRCC7;kinaseDNA-PK |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanDNA-PKaroundthephosphorylationsiteofSer2056. |
ImmunogenRange | 2022-2071 |
Clonality | Polyclonal |
ApplicationDilutions | IHC:1:50~1:100ELISA:1:10000 |
Specificity | DNA-PK(Phospho-Ser2056)AntibodydetectsendogenouslevelsofDNA-PKonlywhenphosphorylatedatSer2056. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | PRKDC |
DatabaseLinks | GeneID: 5591 Swiss-Prot#: P78527 OMIM#: 600899 Unigene#: Hs.491682 |
TargetModification | Phospho |
ModificationSites | H:S2056M:S2053 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbreastcarcinoma,usingDNA-PK(Phospho-Ser2056)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |