The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
HER2 (Phospho-Thr686) Antibody
Synonyms
C-erbB-2, Epidermal growth factor receptor-related protein, ErbB2, HER2, MLN 19, NEU, NEU proto-oncogene, NGL, Receptor protein-tyrosine kinase erbB-2, Receptor protein-tyrosine kinase erbB-2 precursor, Tyrosine kinase-type cell surface receptor HER2, kin
Immunogen
The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Thr686.
Immunogen Range
661-710
Clonality
Polyclonal
Application Dilutions
IF: 1:100~1:500 ELISA: 1:5000
Specificity
HER2 (Phospho-Thr686) Antibody detects endogenous levels of HER2 only when phosphorylated at Thr686.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
ERBB2
Database Links
Gene ID: 2064 Swiss-Prot #: P04626
OMIM #: 164870 Unigene #: Hs.446352
Target Modification
Phospho
Modification Sites
H:T686 M:T687 R:T688
Application Images
Image 1
Immunofluorescence analysis of HUVEC cells, using HER2 (Phospho-Thr686) Antibody. The picture on the right is blocked with the phospho peptide.