Description
Geltrex?LDEV-FreeReducedGrowthFactorBasementMembraneMatrixisasolubleformofbasementmembraneextractedfrommurineEngelbreth-Holm-Swarm(EHS)tumorsandisfreeofviruses,includinglactosedehydrogenaseelevatingvirus(LDEV),sometimesfoundinthistypeofpreparation.ThemajorcomponentsofGeltrex?matrixincludelaminin,collagenIV,entactin,andheparinsulfateproteoglycans.Itisidealforthepromotionandmaintenanceofdifferentiatedphenotypesinavarietyofcellculturesincludingprimaryepithelialcells,endothelialcells,smoothmusclecells,andhumaninducedpluripotentstemcells(iPSC).Geltrex?matrixoffers,onaverage,a2-foldreductioninseveralgrowthfactors.Asaresult,analysisofspecificgrowthfactoreffectsinapplicationsrequiringbasementmembraneextractcanbecarriedoutinacontrolledandreproduc
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KeyFeaturesofGeltrex?LDEV-FreeReducedGrowthFactorBasementMembraneMatrix:?Freeoflactosedehydrogenaseelevatingvirus(LDEV)makingitidealforalltypesofcellcultureandmouse
invivoapplications?Consistentproteinconcentrationlot-to-lothelpsreducetheneedtoscreenlots?Protocolsforvariousapplications,includingtubeformationassays,areavailable
GainReliABIlityandConsistencyinYourhESCStudiesRecentadvancesinprocessingEHStumorcellshaveresultedinvirusfreebasementmembraneextracts.EverylotistestedbyRT-PCRmethodssoyoucannowhaveconfidencethateverylotofGeltrex?isvirusfree.Additionally,ourconsistentmanufacturingprocesshelpsensureaproteinconcentrationwithverylittlevariationfromlot-to-lot,averaging15mg/mlsoyoucanhaveconfidenceineverypurchase.
InvestigateAngiogenesiswithValidatedGibco?ProtocolsTherearemanyapplicationsforGeltrex?LDEV-Freereducedgrowthfactorbasementmembranematrix,eachrequiringdifferentthicknessesandconcentrations.Ingeneral,aproteinconcentrationof