The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
BRCA1 (Phospho-Ser1524) Antibody
Synonyms
BRCA1; Breast cancer type 1 susceptibility protein; familial breast/ovarian cancer gene 1
Immunogen
The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1524.
Immunogen Range
1491-1540
Clonality
Polyclonal
Application Dilutions
IHC: 1:50~1:100 ELISA: 1:10000
Specificity
BRCA1 (Phospho-Ser1524) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1524.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
BRCA1
Database Links
Gene ID: 672 Swiss-Prot #: P38398
OMIM #: 113705/114480 Unigene #: Hs.194143
Target Modification
Phospho
Modification Sites
H:S1524
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using BRCA1 (Phospho-Ser1524) Antibody. The picture on the right is blocked with the phospho peptide.