Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | Synuclein-alpha(Phospho-Tyr133)Antibody |
Synonyms | Alpha-synuclein;Non-AbetacomponentofADamyloid;Non-A4componentofamyloidprecursor;NACP;SNCA;NACP;PARK1 |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanSynuclein-alphaaroundthephosphorylationsiteofTyr133. |
ImmunogenRange | 91-140 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000ELISA:1:40000 |
Specificity | Synuclein-alpha(Phospho-Tyr133)AntibodydetectsendogenouslevelsofSynuclein-alphaonlywhenphosphorylatedatTyr133. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | SNCA |
DatabaseLinks | GeneID: 6622 Swiss-Prot#: P37840 OMIM#: 127750/163890/168600/168601/605543 Unigene#: Hs.271771 |
TargetModification | Phospho |
ModificationSites | H:Y133M:Y133R:Y133 |
ApplicationImages |
Image1 | Westernblotanalysisoflysatesfrom293cellstreatedwithEtoposide25muM60",usingSynuclein-alpha(Phospho-Tyr133)Antibody.Thelaneontheleftisblockedwiththephosphopeptide. |