Description: Goat polyclonal antibody to ADORA2A. It is a member of the guanine nucleotide binding coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular stimuli and activate intracellular signal transduction pathways. It plays an important role in many biological functions, including cerebral and renal blood flow, immune function, cardiac rhythm and circulation, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as neurodegenerative and inflammatory disorders. Alternative names: A2aR, ADORA2, RDC8 antibody.
Form: Polyclonal antibody supplied as a 100 μl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Immunogen: Recombinant peptide derived from within residues 360 aa to the C-terminus of human ADORA2A produced in E. coli.
Specificity: Detects endogenous levels of ADORA2A in brain by Western blot.
Reactivity: Reacts against human, rat, mouse, canine and monkey proteins.
Storage: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
Special instructions: Avoid freeze/thaw cycles.