Immunogen | PurifiedbovineGFAP |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | RecognizesGlialFibrillaryAcidicProtein(GFAP). |
SpeciesReactivity | |
SpeciesReactivityNote | Human,rat,bovineandcanine.ItisexpectedthattheantibodywillreactwithmostmammalianGFAPduetohomology.Reactivitywithotherspecieshasnotbeenconfirmed. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Thisgeneencodesoneofthemajorintermediatefilamentproteinsofmatureastrocytes.Itisusedasamarkertodistinguishastrocytesfromotherglialcellsduringdevelopment.MutationsinthisgenecauseAlexanderdisease,araredisorderofastrocytesinthecentralnervoussystem.Anadditionaltranscriptvarianthasbeendescribed,butitsfulllengthsequencehasnotbeendetermined. |
GeneSymbol | |
PurificationMethod | Unpurified |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q28115#GFAP,aclass-IIIintermediatefilament,isacell-specificmarkerthat,duringthedevelopmentofthecentralnervoussystem,distinguishesastrocytesfromotherglialcells. SIZE:428aminoacids;49512Da SUBCELLULARLOCATION:Cytoplasm.Note=Associatedwithintermediatefilaments. SIMILARITY:SwissProt:Q28115##Belongstotheintermediatefilamentfamily. |
MolecularWeight | 50kDa |