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Millipore/ABN78C3 | Anti-NeuN (rabbit) Antibody, Cy3 Conjugate/ABN78C3/100 µL
  • Millipore/ABN78C3 | Anti-NeuN (rabbit) Antibody, Cy3 Conjugate/ABN78C3/100 µL

Millipore/ABN78C3 | Anti-NeuN (rabbit) Antibody, Cy3 Conjugate/ABN78C3/100 µL

價格: ¥4812.00 市場價: 8020.00

貨號: ABN78C3
品牌: Millipore
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    • Description
      CatalogueNumberABN78C3
      DescriptionAnti-NeuN(rabbit)Antibody,Cy3Conjugate
      AlternateNames
      • NEUronalNuclei
      • NeuronalNuclei
      BackgroundInformationABN78isarabbitpolyclonalversionoftheAnti-NeuN,cloneA60(MAB377),NeuNisahighlycharacterizedandcitedmousemonoclonalantibodythatspecificallyrecognizestheDNA-binding,neuron-specificproteinNeuN,whichispresentinmostCNSandPNSneuronalcelltypesofallvertebratestested.NeuNproteindistributionsareapparentlyrestrictedtoneuronalnuclei,perikaryaandsomeproximalneuronalprocessesinbothfetalandadultbrainalthough,someneuronsfailtoberecognizedbyNeuNatallages:INLretinalcells,Cajal-Retziuscells,Purkinjecells,inferiorolivaryanddentatenucleusneurons,andsympatheticganglioncellsareexamples.ImmunohistochemicallydetectableNeuNproteinfirstappearsatdevelopmentaltimepointsthatcorrespondwiththewithdrawaloftheneuronfromthecellcycleand/orwiththeinitiationofterminaldifferentiationoftheneuron.ImmunoreactivityappearsaroundE9.5inthemouseneuraltubeandisextensivethroughoutthedevelopingnervoussystembyE12.5.Strongnuclearstainingsuggestsanuclearregulatoryproteinfunction;however,noevidencecurrentlyexistsastowhethertheNeuNproteinantigenhasafunctioninthedistalcytoplasmorwhetheritismerelysynthesizedtherebeforebeingtransportedbackintothenucleus.Nodifferencebetweenproteinisolatedfrompurifiednucleiandwholebrainextractonimmunoblotshasbeenfound.
      ProductInformation
      FormatCy3
      Control
      • RatE18cortexcells
      PresentationPurifiedrabbitpolyclonalconjugatedtoCy3inPBSwith0.1%sodiumazideand15mg/mLBSA.
      StorageandShippingInformation
      StorageConditionsMaintainrefrigeratedat2-8°Cprotectedfromlightinundilutedaliquotsforupto6monthsfromdateofreceipt.
      Applications
      ApplicationAnti-NeuN(rabbit)Antibody,Cy3ConjugateisanantibodyagainstNeuN(rabbit)foruseinIC.
      KeyApplications
      • Immunocytochemistry
      BIOLOGicalInformation
      ImmunogenGST-taggedrecombinantproteincorrespondingtomouseNeuN.
      EpitopeN-terminus
      HostRabbit
      SpecificityThisantibodyrecognizesNeuNattheN-terminus.
      SpeciesReactivity
      • Rat
      • Mouse
      SpeciesReactivityNoteDemonstratedtoreactwithMouseandRat.TheunconjugatedrabbitAnti-NeuN(CatalogNo.ABN78)hasbeenshowntoworkinhuman.
      AntibodyTypePolyclonalAntibody
      GeneSymbol
      • NeuN
      PurificationMethodAffinityPurfied
      MolecularWeightTheunconjugatedparentantibody(Cat.No.ABN78)hasanobservedmolecularweightat~46/48kDa.Anuncharacterizedbandappearsat~62kDainsomelysates.
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
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