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Abnova/AADAC monoclonal antibody (M01), clone 2E8/1kit/H00000013-M01
  • Abnova/AADAC monoclonal antibody (M01), clone 2E8/1kit/H00000013-M01

Abnova/AADAC monoclonal antibody (M01), clone 2E8/1kit/H00000013-M01

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貨號(hào): H00000013-M01
品牌: Abnova
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  • 詳情
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  • 常見問題
      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Mouse monoclonal antibody raised against a partial recombinant AADAC.
      • Immunogen:
      • AADAC (NP_001077, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
      • Sequence:
      • QLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFINWSSLLPERFIKGHVYNNP
      • Host:
      • Mouse
      • Reactivity:
      • Human
      • Isotype:
      • IgG2b Kappa
      • Quality Control Testing:
      • Antibody Reactive Against Recombinant Protein.QC Testing of H00000013-M01Western Blot detection against Immunogen (36.74 KDa) .
      • Storage Buffer:
      • In 1x PBS, pH 7.4
      • Storage Instruction:
      • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
      • MSDS:
      • PDF DownloadDownload
      • Interspecies Antigen Sequence:
      • Mouse (73); Rat (69)
      • Datasheet:
      • PDF DownloadDownload
      • Publication Reference
      • 1.
      • N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity.Muta K, Fukami T, Nakajima M, Yokoi TBiochem Pharmacol. 2013 Oct 11. pii: S0006-2952(13)00651-5. doi: 10.1016/j.bcp.2013.10.001.
      • 2.
      • Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia.Kobayashi Y, Fukami T, Higuchi R, Nakajima M, Yokoi T.Biochem Pharmacol. 2012 Aug 23.
      • 3.
      • A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Diminished Enzyme Activity.Shimizu M, Fukami T, Kobayashi Y, Takamiya M, Aoki Y, Nakajima M, Yokoi T.Drug Metab Dispos. 2012 Mar 13. [Epub ahead of print]
      • 4.
      • Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse.Kobayashi Y, Fukami T, Nakajima A, Watanabe A, Nakajima M, Yokoi T.Drug Metab Dispos. 2012 Apr;40(4):671-9. Epub 2011 Dec 29.
      • 5.
      • Human Arylacetamide Deacetylase Is A Principal Enzyme in Flutamide Hydrolysis.Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T.Drug Metab Dispos. 2009 Jul;37(7):1513-20. Epub 2009 Apr 1.
      • Applications
      • Western Blot (Recombinant protein)
      • PDF DownloadProtocol Download
      • Sandwich ELISA (Recombinant protein)
      • Sandwich ELISA (Recombinant protein)
      • Detection limit for recombinant GST tagged AADAC is approximately 3ng/ml as a capture antibody.
      • PDF DownloadProtocol Download
      • ELISA
      • Application Image
      • Western Blot (Recombinant protein)
      • Sandwich ELISA (Recombinant protein)
      • Sandwich ELISA (Recombinant protein)
      • enlarge
      • ELISA
      • Gene Information
      • Entrez GeneID:
      • 13
      • GeneBank Accession#:
      • NM_001086
      • Protein Accession#:
      • NP_001077
      • Gene Name:
      • AADAC
      • Gene Alias:
      • CES5A1,DAC
      • Gene Description:
      • arylacetamide deacetylase (esterase)
      • Omim ID:
      • 600338
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq
      • Other Designations:
      • arylacetamide deacetylase
      • Gene Pathway
      • Tropane, piperidine and pyridine alkaloid biosynthesis
      • Related Disease
      • Tobacco Use Disorder
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