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Abnova/ABCC8 purified MaxPab mouse polyclonal antibody (B01P)/1kit/H00006833-B01P
  • Abnova/ABCC8 purified MaxPab mouse polyclonal antibody (B01P)/1kit/H00006833-B01P

Abnova/ABCC8 purified MaxPab mouse polyclonal antibody (B01P)/1kit/H00006833-B01P

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貨號: H00006833-B01P
品牌: Abnova
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  • 詳情
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  • 常見問題
      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Mouse polyclonal antibody raised against a full-length human ABCC8 protein.
      • Immunogen:
      • ABCC8 (AAI67829.1, 1 a.a. ~ 1581 a.a) full-length human protein.
      • Sequence:
      • MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK
      • Host:
      • Mouse
      • Reactivity:
      • Human
      • Quality Control Testing:
      • Antibody reactive against mammalian transfected lysate.
      • Storage Buffer:
      • In 1x PBS, pH 7.4
      • Storage Instruction:
      • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
      • MSDS:
      • PDF DownloadDownload
      • Interspecies Antigen Sequence:
      • Mouse (94); Rat (95)
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Transfected lysate)
      • PDF DownloadProtocol Download
      • Application Image
      • Western Blot (Transfected lysate)
      • Gene Information
      • Entrez GeneID:
      • 6833
      • GeneBank Accession#:
      • BC167829.1
      • Protein Accession#:
      • AAI67829.1
      • Gene Name:
      • ABCC8
      • Gene Alias:
      • ABC36,HHF1,HI,HRINS,MRP8,PHHI,SUR,SUR1,TNDM2
      • Gene Description:
      • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
      • Omim ID:
      • 125853, 240800, 256450, 600509, 606176, 610374
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq
      • Other Designations:
      • ATP-binding cassette, sub-family C, member 8,sulfonylurea receptor (hyperinsulinemia)
      • Gene Pathway
      • ABC transporters
      • Type II diabetes mellitus
      • Related Disease
      • Adenocarcinoma
      • Alzheimer Disease
      • Alzheimer disease
      • Atherosclerosis
      • Cardiovascular Diseases
      • Cerebrovascular Accident
      • Chronic Disease
      • Diabetes Complications
      • Diabetes Mellitus
      • Diabetes Mellitus, Type 1
      • Diabetes Mellitus, Type 2
      • Diabetes, Gestational
      • Diabetic Angiopathies
      • Disease Progression
      • Drug Toxicity
      • Edema
      • Esophageal Neoplasms
      • Genetic Predisposition to Disease
      • Glucose Intolerance
          • ... see more
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