ACTA1/ACTC1/ACTG1/ACTG2 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of ACTA1/ACTC1/ACTG1/ACTG2 expression in cultured cells.
P68032 (Gene ID : 58);P63261 (Gene ID : 70);P63267 (Gene ID : 71);P68133 (Gene ID : 72)
Gene Name:
ACTA1
Gene Alias:
ACTA,ASMA,CFTD,CFTD1,CFTDM,MPFD,NEM1,NEM2,NEM3
Gene Description:
actin, alpha 1, skeletal muscle
Omim ID:
102610, 161800, 255310
Gene Ontology:
Hyperlink
Gene Summary:
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq
Other Designations:
OTTHUMP00000036123,alpha skeletal muscle actin
Gene Information
Entrez GeneID:
70
Protein Accession#:
P68032 (Gene ID : 58);P63261 (Gene ID : 70);P63267 (Gene ID : 71);P68133 (Gene ID : 72)
Gene Name:
ACTC1
Gene Alias:
ACTC,CMD1R,CMH11
Gene Description:
actin, alpha, cardiac muscle 1
Omim ID:
102540, 192600
Gene Ontology:
Hyperlink
Gene Summary:
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq
Other Designations:
cardiac muscle alpha actin 1
Gene Information
Entrez GeneID:
71
Protein Accession#:
P68032 (Gene ID : 58);P63261 (Gene ID : 70);P63267 (Gene ID : 71);P68133 (Gene ID : 72)
Gene Name:
ACTG1
Gene Alias:
ACT,ACTG,DFNA20,DFNA26
Gene Description:
actin, gamma 1
Omim ID:
102560, 604717
Gene Ontology:
Hyperlink
Gene Summary:
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton.In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility.Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells. [provided by RefSeq
P68032 (Gene ID : 58);P63261 (Gene ID : 70);P63267 (Gene ID : 71);P68133 (Gene ID : 72)
Gene Name:
ACTG2
Gene Alias:
ACT,ACTA3,ACTE,ACTL3,ACTSG
Gene Description:
actin, gamma 2, smooth muscle, enteric
Omim ID:
102545
Gene Ontology:
Hyperlink
Gene Summary:
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton.In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility.Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues. [provided by RefSeq