The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
Cdk5 (Phospho-Tyr15) Antibody
Synonyms
Cyclin-dependent kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human Cdk5 around the phosphorylation site of Tyr15.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
Cdk5 (Phospho-Tyr15) antibody detects endogenous levels of Cdk5 only when phosphorylated at Tyr15.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
CDK5
Database Links
Gene ID: 1020 Swiss-Prot #: Q00535
OMIM #: 123831 Unigene #: Hs.647078
Target Modification
Phospho
Modification Sites
H:Y15, M:Y15, R:Y15
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Cdk5 (Phospho-Tyr15) Antibody
Image 2
Western blot analysis of lysates from HT29 cells treated with PMA, using p-Cdk5 (Phospho-Tyr15) antibody.