The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
PTP1B (Phospho-Ser352) Antibody
Synonyms
Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human PTP1B around the phosphorylation site of Ser352.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
PTP1B (Phospho-Ser352) antibody detects endogenous levels of PTP1B only when phosphorylated at Ser352.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
PTPN1
Database Links
Gene ID: 5770 Swiss-Prot #: P18031
OMIM #: 176885 Unigene #: Hs.417549
Target Modification
Phospho
Modification Sites
H:S352
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PTP1B (Phospho-Ser352) Antibody
Image 2
Western blot analysis of lysates from COS7 cells treated with UV, using p-PTP1B (Phospho-Ser352) antibody.