The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
PKA-R2beta (Phospho-Ser113) Antibody
Synonyms
KAP3; PKA R2-beta; PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory chain
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human PKA-R2beta around the phosphorylation site of Ser113.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
PKA-R2beta (Phospho-Ser113) Antibody detects endogenous levels of PRKAR2B only when phosphorylated at Ser113.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
PRKAR2B
Database Links
Gene ID: 5577 Swiss-Prot #: P31323
OMIM #: 176912 Unigene #: Hs.433068
Target Modification
Phospho
Modification Sites
H:S113, M:S111, R:S111
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PKA-R2β (Phospho-Ser113) Antibody
Image 2
Western blot analysis of lysates from COS7 cells treated with PMA 125ng/ml 30', using PKA-R2 beta (Phospho-Ser113) Antibody.