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Abnova/AAK1 polyclonal antibody/1kit/PAB16581
  • Abnova/AAK1 polyclonal antibody/1kit/PAB16581

Abnova/AAK1 polyclonal antibody/1kit/PAB16581

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貨號(hào): PAB16581
品牌: Abnova
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  • 詳情
  • 使用說(shuō)明
  • 常見(jiàn)問(wèn)題
      • Specification
      • Gene Info
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Rabbit polyclonal antibody raised against synthetic peptide of AAK1.
      • Immunogen:
      • A synthetic peptide corresponding to N-terminus 20 amino acids of human AAK1.
      • Host:
      • Rabbit
      • Reactivity:
      • Human, Mouse, Rat
      • Form:
      • Liquid
      • Recommend Usage:
      • Western Blot (1-2 ug/mL)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (0.02% sodium azide)
      • Storage Instruction:
      • Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Publication Reference
      • 1.
      • A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.Henderson DM, Conner SD.Mol Biol Cell. 2007 Jul;18(7):2698-706. Epub 2007 May 9.
      • 2.
      • The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton.Smythe E, Ayscough KR.EMBO Rep. 2003 Mar;4(3):246-51.
      • 3.
      • Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis.Conner SD, Schmid SL.J Cell Biol. 2002 Mar 4;156(5):921-9. Epub 2002 Mar 4.
      • Applications
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • Western blot analysis of AAK1 in A-20 cell lysate with AAK1 polyclonal antibody (Cat # PAB16581) at (A) 1 and (B) 2 ug/mL .
      • Immunocytochemistry
      • Immunocytochemistry
      • Immunocytochemistry of AAK1 in A-20 cells with AAK1 polyclonal antibody (Cat # PAB16581) at 5 ug/mL .
      • Enzyme-linked Immunoabsorbent Assay
      • Application Image
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • enlarge
      • Immunocytochemistry
      • Immunocytochemistry
      • enlarge
      • Enzyme-linked Immunoabsorbent Assay
      • Gene Information
      • Entrez GeneID:
      • 22848
      • Protein Accession#:
      • NP_055726
      • Gene Name:
      • AAK1
      • Gene Alias:
      • DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
      • Gene Description:
      • AP2 associated kinase 1
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
      • Other Designations:
      • adaptor-associated kinase 1
      • Related Disease
      • Parkinson Disease
      • Tobacco Use Disorder
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