Goat polyclonal antibody raised against native human A2M.
Immunogen:
Native purified human A2M.
Host:
Goat
Reactivity:
Human
Specificity:
This product reacts with alpha 2-macroglobulin in serum. It does not react with Human IgM, IgA, or IgG by IEP analysis.
Form:
Liquid
Purification:
Antigen Affinity Purified
Isotype:
IgG
Recommend Usage:
ELISA (2 ug/mL)Western Blot (0.05-0.5 ug/mL)The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.2 (0.09 % sodium azide)
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
Download
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of A2M polyclonal antibody (Cat# PAB29771) under 2 ug/mL working concentration.
Application Image
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Information
Entrez GeneID:
2
GeneBank Accession#:
P01023
Gene Name:
A2M
Gene Alias:
CPAMD5,DKFZp779B086,FWP007,S863-7
Gene Description:
alpha-2-macroglobulin
Omim ID:
103950, 104300
Gene Ontology:
Hyperlink
Gene Summary:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations:
-
Interactome
Gene Pathway
Complement and coagulation cascades
Related Disease
Alzheimer Disease
Alzheimer disease
Amyloidosis
Arthritis, Rheumatoid
Cardiovascular Diseases
Cognition Disorders
Dementia
Diabetes Complications
Diabetes Mellitus, Type 2
Disease Progression
Diseases in Twins
Edema
Essential Tremor
Essential tremor
Genetic Predisposition to Disease
Hepatitis C, Chronic
Kidney Failure, Chronic
Liver Cirrhosis
Macular Degeneration
... see more
Memory Disorders
Metabolic Syndrome X
Multiple Sclerosis
Myocardial Infarction
Neoplasms
Obesity
Obesity
Osteoporosis
Parkinson Disease
Parkinson disease
... hidden
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