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Abnova/ADAM17 (phospho T735) polyclonal antibody/1kit/PAB31643
  • Abnova/ADAM17 (phospho T735) polyclonal antibody/1kit/PAB31643

Abnova/ADAM17 (phospho T735) polyclonal antibody/1kit/PAB31643

價(jià)格: 試用 市場(chǎng)價(jià): 0.00
貨號(hào): PAB31643
品牌: Abnova
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  • 常見問題
      • Specification
      • Gene Info
      • Interactome
      • Pathway
      • Disease
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      • Specification
      • Product Description:
      • Rabbit polyclonal antibody raised against synthetic peptide of human ADAM17 (phospho T735).
      • Immunogen:
      • A synthetic peptide corresponding to amino acids 670-750 of human ADAM17 (phospho T735).
      • Host:
      • Rabbit
      • Reactivity:
      • Human, Mouse, Rat
      • Specificity:
      • This antibody detects endogenous levels of ADAM17 protein only when phosphorylated at T735.
      • Form:
      • Liquid
      • Purification:
      • Affinity purification
      • Isotype:
      • IgG
      • Recommend Usage:
      • ELISA (1:20000)Immunohistochemistry (1:100-300)Western Blot (1:500-2000)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (50% glycerol, 0.5% BSA and 0.02% sodium azide).
      • Storage Instruction:
      • Store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot
      • Immunohistochemistry
      • Enzyme-linked Immunoabsorbent Assay
      • Application Image
      • Western Blot
      • Immunohistochemistry
      • Enzyme-linked Immunoabsorbent Assay
      • Gene Information
      • Entrez GeneID:
      • 6868
      • Protein Accession#:
      • P78536
      • Gene Name:
      • ADAM17
      • Gene Alias:
      • CD156b,MGC71942,TACE,cSVP
      • Gene Description:
      • ADAM metallopeptidase domain 17
      • Omim ID:
      • 603639
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq
      • Other Designations:
      • TNF-alpha converting enzyme,a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme),snake venom-like protease,tumor necrosis factor, alpha, converting enzyme
      • Interactome
      • Interactome
      • Gene Pathway
      • Alzheimer"s disease
      • Epithelial cell signaling in Helicobacter pylori infection
      • Notch signaling pathway
      • Related Disease
      • Alzheimer Disease
      • Arthritis, Rheumatoid
      • Breast cancer
      • Breast Neoplasms
      • Cardiovascular Diseases
      • Chronic Disease
      • Cleft Lip
      • Cleft Palate
      • Coronary Artery Disease
      • Crohn Disease
      • Crohn"s disease
      • Diabetes Mellitus
      • Diabetes Mellitus, Type 2
      • Edema
      • Genetic Predisposition to Disease
      • Lymphoma, Non-Hodgkin
      • Myocardial Infarction
      • Peripheral Vascular Diseases
      • Tobacco Use Disorder
          • ... see more
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