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Abnova/Amyloid beta 4-10 recombinant monoclonal antibody, clone WO2/1kit/RAB00070
  • Abnova/Amyloid beta 4-10 recombinant monoclonal antibody, clone WO2/1kit/RAB00070

Abnova/Amyloid beta 4-10 recombinant monoclonal antibody, clone WO2/1kit/RAB00070

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貨號(hào): RAB00070
品牌: Abnova
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  • 詳情
  • 使用說明
  • 常見問題
      • Specification
      • Product Description:
      • Recombinant mouse monoclonal antibody raised against human Amyloid beta 4-10.
      • Immunogen:
      • Original antibody is raised against a synthetic peptide of human Amyloid beta.
      • Reactivity:
      • Human
      • Specificity:
      • This antibody recognizes acid residues 4-10 of human Amyloid beta.
      • Form:
      • Liquid
      • Purification:
      • Protein A affinity purification
      • Isotype:
      • IgG2a, kappa
      • Recommend Usage:
      • ELISA (0.1 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)Western Blot (1 ug/mL)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS, pH 7.2 (0.02% Proclin 300).
      • Storage Instruction:
      • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Antibody Species:
      • Mouse
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Enzyme-linked Immunoabsorbent Assay
      • Application Image
      • Western Blot
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Enzyme-linked Immunoabsorbent Assay
      • Gene Information
      • Entrez GeneID:
      • 351
      • Protein Accession#:
      • P05067
      • Gene Name:
      • APP
      • Gene Alias:
      • AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2
      • Gene Description:
      • amyloid beta (A4) precursor protein
      • Omim ID:
      • 104760, 605714
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
      • Other Designations:
      • A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide,peptidase nexin-II,protease nexin-II
      • Interactome
      • Interactome
      • Gene Pathway
      • Alzheimer"s disease
      • Related Disease
      • Alzheimer Disease
      • Alzheimer disease
      • Amyloidosis, Familial
      • Cardiovascular Diseases
      • Celiac Disease
      • Cerebral Hemorrhage
      • Cerebrovascular Disorders
      • Cognition
      • Cognition Disorders
      • Dementia
      • Diabetes Mellitus, Type 2
      • Disease Progression
      • Disease Susceptibility
      • Down Syndrome
      • Edema
      • Genetic Predisposition to Disease
      • Headache
      • Macular Degeneration
      • Mental Status Schedule
        • ... see more
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